Common Guinea Pig Diseases: What Owners Should Know
Guinea pigs are prone to specific health issues including vitamin C deficiency, respiratory infections, and dental problems.
Guinea pigs make wonderful pets but are prone to several specific diseases that owners should recognize early. Unlike many mammals, guinea pigs cannot synthesize their own vitamin C and must obtain it from their diet. Dental problems, respiratory disease, and parasites are also common. RVC provides care for guinea pigs and other small mammals. Call +853 6677 6611.
Key Points
- Guinea pigs cannot make their own vitamin C — dietary intake is essential
- Vitamin C deficiency causes scurvy: joint pain, bleeding gums, poor coat
- Dental disease is common due to continuously growing teeth
- Respiratory infections are often caused by Bordetella or Streptococcus
- Mites (Trixacarus caviae) cause intense itching and hair loss
- Guinea pigs hide illness well — subtle changes indicate serious problems
Vitamin C Deficiency (Scurvy)
Guinea pigs need 10-30mg of vitamin C daily (more if pregnant or ill). Good sources: bell peppers, parsley, kale, broccoli, and guinea pig pellets fortified with vitamin C (but vitamin C degrades within 90 days of opening the bag). Signs of deficiency: rough hair coat, lethargy, swollen joints, bleeding gums, reluctance to move, and bruising. Treatment: oral vitamin C supplementation and dietary improvement. Injectable vitamin C may be needed for severe cases.
Dental Disease
Guinea pig teeth grow continuously throughout life. Proper wear requires unlimited hay (timothy, orchard grass) — hay provides the abrasive fiber needed to grind teeth down. Signs of dental problems: drooling, wet chin (slobbers), difficulty eating, weight loss, dropping food, and favoring one side of the mouth. Overgrown molars can develop sharp spurs that cut the tongue and cheeks. Treatment: trimming or filing teeth under anesthesia by an experienced vet.
Respiratory Infections
Guinea pigs are susceptible to bacterial respiratory infections, especially Bordetella bronchiseptica and Streptococcus pneumoniae. Stress, poor ventilation, and overcrowding increase risk. Signs include: sneezing, nasal discharge, coughing, wheezing, labored breathing, and lethargy. URI can progress to pneumonia quickly. Treatment requires antibiotics safe for guinea pigs (not all are — penicillin and some others are toxic). Supportive care includes nebulization, fluids, and nutritional support.
Parasites and Skin Problems
Trixacarus caviae (mange mites) cause severe itching, hair loss, crusting, and seizures in heavy infestations. Diagnosed with skin scrapings or tape preps. Treatment: ivermectin or selamectin. Lice (Gliricola porcelli, Gyropus ovalis) cause milder itching and are species-specific (don't affect humans). Fungal infections (ringworm, Trichophyton mentagrophytes) cause circular patches of hair loss with scaling. Guinea pigs can carry Bordetella without symptoms but transmit it to rabbits (which can be fatal).
When to See a Vet Immediately
- Not eating or drinking for 24 hours
- Weight loss or ribs/spine becoming prominent
- Difficulty breathing, sneezing, or nasal discharge
- Excessive itching, hair loss, or skin crusting
- Lethargy or hiding more than usual
- Soft stool or diarrhea persisting more than 24 hours
How RVC Can Help
RVC provides care for guinea pigs and other exotic pets. If your guinea pig seems unwell, don't wait — small pets decline rapidly. Call +853 6677 6611.
This article is for educational purposes only and does not replace professional veterinary advice. If your pet is showing any symptoms, please contact Royal Veterinary Center immediately at +853 6677 6611.